Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Q96EB6 sirtuin 1 Epigenetic regulator 675 0.378 0.885 8.7E-02 0.070 None 1.000 7 0 2017 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Q16236 nuclear factor, erythroid 2 like 2 Enzyme 823 0.357 0.885 3.6E-03 0.350 None 1.000 6 0 2010 2019
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
Q07869 peroxisome proliferator activated receptor alpha Nuclear receptor 408 0.432 0.885 3.0E-02 0.050 None 1.000 5 0 2013 2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
Q96P20 NLR family pyrin domain containing 3 805 0.361 0.962 8.1E-04 0.050 None 1.000 5 0 2017 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 2724 0.231 0.962 0.80 0.340 None 1.000 5 0 2010 2019
Entrez Id: 84182
Gene Symbol: MINDY4
MINDY4
Q4G0A6 MINDY lysine 48 deubiquitinase 4 122 0.538 0.731 3.2E-19 0.040 None 1.000 4 0 2014 2019
Entrez Id: 151306
Gene Symbol: GPBAR1
GPBAR1
Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 122 0.548 0.731 1.4E-09 0.040 None 1.000 4 0 2013 2019
Entrez Id: 358
Gene Symbol: AQP1
AQP1
P29972 aquaporin 1 (Colton blood group) Ion channel 268 0.467 0.885 2.6E-07 0.040 None 1.000 4 0 2014 2019
Entrez Id: 847
Gene Symbol: CAT
CAT
P04040 catalase Enzyme 794 0.359 0.962 1.6E-10 0.520 None 1.000 4 0 2011 2019
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 420 0.419 0.885 2.1E-32 0.040 None 1.000 4 0 2006 2019
Entrez Id: 84565
Gene Symbol: LCS1
LCS1
lymphedema-cholestasis syndrome 1 14 0.780 0.269 0.030 None 1.000 3 0 2003 2019
Entrez Id: 7421
Gene Symbol: VDR
VDR
P11473 vitamin D receptor Nuclear receptor 852 0.352 0.885 1.7E-05 0.030 None 1.000 3 0 2012 2019
Entrez Id: 4316
Gene Symbol: MMP7
MMP7
P09237 matrix metallopeptidase 7 Enzyme 320 0.446 0.885 1.0E-09 0.030 None 1.000 3 0 2017 2019
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
P18146 early growth response 1 Nucleic acid binding 378 0.433 0.923 0.35 0.320 None 1.000 3 0 2011 2019
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
Q06546 GA binding protein transcription factor subunit alpha Transcription factor 632 0.379 0.885 1.00 0.030 None 1.000 3 0 2017 2019
Entrez Id: 26503
Gene Symbol: SLC17A5
SLC17A5
Q9NRA2 solute carrier family 17 member 5 Transporter 252 0.491 0.808 6.9E-10 0.020 None 1.000 2 0 2017 2019
Entrez Id: 4988
Gene Symbol: OPRM1
OPRM1
P35372 opioid receptor mu 1 G-protein coupled receptor 370 0.457 0.808 7.9E-11 0.020 None 1.000 2 1 2008 2019
Entrez Id: 57410
Gene Symbol: SCYL1
SCYL1
Q96KG9 SCY1 like pseudokinase 1 Kinase 104 0.582 0.769 2.5E-08 0.020 None 1.000 2 0 2018 2019
Entrez Id: 5725
Gene Symbol: PTBP1
PTBP1
P26599 polypyrimidine tract binding protein 1 172 0.517 0.769 1.00 0.020 None 1.000 2 0 2017 2019
Entrez Id: 54532
Gene Symbol: USP53
USP53
Q70EK8 ubiquitin specific peptidase 53 Enzyme 2 1.000 0.038 1.7E-13 0.010 None 1.000 1 0 2019 2019
Entrez Id: 494327
Gene Symbol: MIR378A
MIR378A
microRNA 378a 127 0.532 0.808 0.010 None 1.000 1 0 2019 2019
Entrez Id: 5730
Gene Symbol: PTGDS
PTGDS
P41222 prostaglandin D2 synthase Enzyme 195 0.503 0.846 5.1E-03 0.010 None 1.000 1 0 2019 2019
Entrez Id: 50507
Gene Symbol: NOX4
NOX4
Q9NPH5 NADPH oxidase 4 Enzyme 260 0.471 0.885 5.8E-20 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6283
Gene Symbol: S100A12
S100A12
P80511 S100 calcium binding protein A12 Calcium-binding protein 221 0.488 0.846 0.48 0.010 None 1.000 1 0 2019 2019
Entrez Id: 1869
Gene Symbol: E2F1
E2F1
Q01094 E2F transcription factor 1 Nucleic acid binding 324 0.441 0.846 0.99 0.010 None 1.000 1 0 2019 2019